Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity related to bortezomib, a proteasome inhibitor Employed in the treatment of various myeloma. Its synthesis or review is important for making certain the purity and safety of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor inside the synthesis of abiraterone acetate, a drug used in the cure of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-1): A essential compound while in the synthesis of imatinib, a drug that targets certain kinds of cancer, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers including breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are intermediates while in the synthesis of gemcitabine, an anti-cancer drug. Their review is essential for optimizing the generation process and making certain Paclitaxel side chain acid superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is used to treat breast cancer, and these intermediates are involved in its generation.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Utilized in the procedure of breast most cancers. Numerous intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug successful in dealing with cancers which include ovarian, breast, and lung most cancers.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the D-Gluconic acid remedy of colorectal cancer and little mobile lung most cancers.
three-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved with the synthesis of adamantane derivatives, that have several purposes, including antiviral Qualities.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for sort 2 diabetes that inhibits the enzyme DPP-four to control blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is involved in the synthesis of varied gluconic acid derivatives, that happen to be Utilized in foods, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor in the synthesis of canagliflozin, a medication used to manage type two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).